Hazardous Chemical Information System (HCIS)



Hazardous Chemical Details

Cas Number 86347-14-0
Chemical Name (RS)-4-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
Chemical Synonym medetomidine
Hazard Category Acute toxicity (inhalation) - category 2
Acute toxicity (ingestion) - category 2
Specific target organ toxicity (single exposure) – category 3
Specific target organ toxicity (single exposure) – category 1
Specific target organ toxicity (repeated exposure) – category 1
Hazardous to the aquatic environment (acute) – category 1
Hazardous to the aquatic environment (chronic) – category 1
Hazard Statement H330 (Fatal if inhaled)
H300 (Fatal if swallowed)
H336 (May cause drowsiness or dizziness)
H370 (Cause damage to eyes)
H372 (Causes damage to organs through prolonged or repeated exposure)
H410 (Very toxic to aquatic life with long-lasting effects)
Pictogram Pictogram of Skull and Crossbones GHS06 (Skull and Crossbones)
Pictogram of Health Hazard GHS08 (Health Hazard)
Pictogram of Environment GHS09 (Environment)
Signal Word Danger
Cut-offs

M = 1 (acute)
M = 100 (chronic)

Notes 8 (The tables in schedule 6 of the WHS regulations replace some tables in the GHS, this may affect the cut off concentrations for this chemical.)
Sources EU (Classification information for chemical is taken from the European Union’s Classification, Labelling and Packaging (CLP) Regulation.)

Hazardous Chemical History

Date Description
08/04/2022 Hazard Category modified from
[HC065:Acute toxicity (inhalation) - category 2,
HC070:Acute toxicity (ingestion) - category 2,
HC110:Specific target organ toxicity (single exposure) – category 3,
HC108:Specific target organ toxicity (single exposure) – category 1,
HC111:Specific target organ toxicity (repeated exposure) – category 1,
HC115:Hazardous to the aquatic environment (acute) – category 1,
HC118:Hazardous to the aquatic environment (chronic) – category 1]

to
[HC065:Acute toxicity (inhalation) - category 2,
HC070:Acute toxicity (ingestion) - category 2,
HC108:Specific target organ toxicity (single exposure) – category 1,
HC110:Specific target organ toxicity (single exposure) – category 3,
HC111:Specific target organ toxicity (repeated exposure) – category 1,
HC115:Hazardous to the aquatic environment (acute) – category 1,
HC118:Hazardous to the aquatic environment (chronic) – category 1]

Hazard Statement modified from
[H330 Fatal if inhaled;
H300 Fatal if swallowed;
H336 May cause drowsiness or dizziness;
H370 May cause damage to eyes;
H372 Causes damage to organs through prolonged or repeated exposure;
H410 Very toxic to aquatic life with long-lasting effects]
to
[H330 Fatal if inhaled;
H300 Fatal if swallowed;
H336 May cause drowsiness or dizziness;
H370 Cause damage to eyes;
H372 Causes damage to organs through prolonged or repeated exposure;
H410 Very toxic to aquatic life with long-lasting effects]
Notes modified from
[]
to
[8 ]
08/04/2022 CutOffs modified from
[]
to
[

M = 1 (acute)
M = 100 (chronic)

]
Hazard Category modified from
[HC060:Acute toxicity – category 2,
HC108:Specific target organ toxicity (single exposure) – category 1,
HC110:Specific target organ toxicity (single exposure) – category 3,
HC111:Specific target organ toxicity (repeated exposure) – category 1,
HC115:Hazardous to the aquatic environment (acute) – category 1,
HC118:Hazardous to the aquatic environment (chronic) – category 1]

to
[HC065:Acute toxicity (inhalation) - category 2,
HC070:Acute toxicity (ingestion) - category 2,
HC108:Specific target organ toxicity (single exposure) – category 1,
HC110:Specific target organ toxicity (single exposure) – category 3,
HC111:Specific target organ toxicity (repeated exposure) – category 1,
HC115:Hazardous to the aquatic environment (acute) – category 1,
HC118:Hazardous to the aquatic environment (chronic) – category 1]
21/03/2019 Chemical Added