Hazardous Chemical Information System (HCIS)



Hazardous Chemical Details

Cas Number 636-23-7
Chemical Name 1,3-Benzenediamine, 4-methyl-, dihydrochloride
Chemical Synonym toluene-2,4-diamine, dihydrochloride
2,4-diaminotoluene dihydrochloride
4-methyl-m-phenylenediamine dihydrochloride
2,4-toluenediamine dihydrochloride
Hazard Category Skin sensitisation – category 1
Germ cell mutagenicity – category 2
Carcinogenicity – category 1B
Reproductive toxicity – category 2
Specific target organ toxicity (repeated exposure) – category 2
Acute toxicity (ingestion) - category 3
Acute toxicity (dermal) - category 4
Hazard Statement H317 (May cause an allergic skin reaction)
H341 (Suspected of causing genetic defects)
H350 (May cause cancer)
H361 (Suspected of damaging fertility or the unborn child)
H373 (May cause damage to organs through prolonged or repeated exposure)
H301 (Toxic if swallowed)
H312 (Harmful in contact with skin)
Pictogram Pictogram of Skull and Crossbones GHS06 (Skull and Crossbones)
Pictogram of Health Hazard GHS08 (Health Hazard)
Signal Word Danger
Cut-offs
Notes 8 (The tables in schedule 6 of the WHS regulations replace some tables in the GHS, this may affect the cut off concentrations for this chemical.)
Sources A (The classification information for this entry was provided by the Australian Industrial Chemicals Introduction Scheme)

Hazardous Chemical History

Date Description
18/08/2021 Synonym modified from
[]
to
[toluene-2,4-diamine, dihydrochloride ;
2,4-diaminotoluene dihydrochloride ;
4-methyl-m-phenylenediamine dihydrochloride ;
2,4-toluenediamine dihydrochloride]
Hazard Category modified from
[HC092:Skin sensitisation – category 1,
HC098:Germ cell mutagenicity – category 2,
HC101:Carcinogenicity – category 1B,
HC106:Reproductive toxicity – category 2,
HC112:Specific target organ toxicity (repeated exposure) – category 2,
HC071:Acute toxicity (ingestion) - category 3,
HC077:Acute toxicity (dermal) - category 4]

to
[HC071:Acute toxicity (ingestion) - category 3,
HC077:Acute toxicity (dermal) - category 4,
HC092:Skin sensitisation – category 1,
HC098:Germ cell mutagenicity – category 2,
HC101:Carcinogenicity – category 1B,
HC106:Reproductive toxicity – category 2,
HC112:Specific target organ toxicity (repeated exposure) – category 2]
18/08/2021 Hazard Category modified from
[HC061:Acute toxicity – category 3,
HC062:Acute toxicity – category 4,
HC092:Skin sensitisation – category 1,
HC098:Germ cell mutagenicity – category 2,
HC101:Carcinogenicity – category 1B,
HC106:Reproductive toxicity – category 2,
HC112:Specific target organ toxicity (repeated exposure) – category 2]

to
[HC071:Acute toxicity (ingestion) - category 3,
HC077:Acute toxicity (dermal) - category 4,
HC092:Skin sensitisation – category 1,
HC098:Germ cell mutagenicity – category 2,
HC101:Carcinogenicity – category 1B,
HC106:Reproductive toxicity – category 2,
HC112:Specific target organ toxicity (repeated exposure) – category 2]

Hazard Statement modified from
[H301 Toxic if swallowed;
H312 Harmful in contact with skin;
H317 May cause an allergic skin reaction;
H341 Suspected of causing genetic defects;
H350 May cause cancer;
H361 Suspected of damaging fertility or the unborn child;
H373 May cause damage to organs through prolonged or repeated exposure]
to
[H317 May cause an allergic skin reaction;
H341 Suspected of causing genetic defects;
H350 May cause cancer;
H361 Suspected of damaging fertility or the unborn child;
H373 May cause damage to organs through prolonged or repeated exposure;
H301 Toxic if swallowed;
H312 Harmful in contact with skin]
Sources modified from
[N]
to
[A]
09/05/2018 Chemical Added