Hazardous Chemical Information System (HCIS)



Hazardous Chemical Details

Cas Number 1464-53-5
Chemical Name 2,2'-bioxirane
Chemical Synonym 1,2:3,4-diepoxybutane
Hazard Category Carcinogenicity – category 1B
Germ cell mutagenicity – category 1B
Skin corrosion – category 1B
Acute toxicity (inhalation) - category 2
Acute toxicity (dermal) - category 3
Acute toxicity (ingestion) - category 3
Hazard Statement H350 (May cause cancer)
H340 (May cause genetic defects)
H314 (Causes severe skin burns and eye damage)
H330 (Fatal if inhaled)
H311 (Toxic in contact with skin)
H301 (Toxic if swallowed)
Pictogram Pictogram of Skull and Crossbones GHS06 (Skull and Crossbones)
Pictogram of Health Hazard GHS08 (Health Hazard)
Pictogram of Corrosion GHS05 (Corrosion)
Signal Word Danger
Cut-offs
Notes 8 (The tables in schedule 6 of the WHS regulations replace some tables in the GHS, this may affect the cut off concentrations for this chemical.)
Sources EU (Classification information for chemical is taken from the European Union’s Classification, Labelling and Packaging (CLP) Regulation.)

Hazardous Chemical History

Date Description
18/08/2021 Hazard Category modified from
[HC101:Carcinogenicity – category 1B,
HC097:Germ cell mutagenicity – category 1B,
HC060:Acute toxicity – category 2,
HC061:Acute toxicity – category 3,
HC081:Skin corrosion – category 1B]

to
[HC065:Acute toxicity (inhalation) - category 2,
HC071:Acute toxicity (ingestion) - category 3,
HC076:Acute toxicity (dermal) - category 3,
HC081:Skin corrosion – category 1B,
HC097:Germ cell mutagenicity – category 1B,
HC101:Carcinogenicity – category 1B]

Pictogram modified from
[GHS06,GHS08,GHS05]
to
[GHS05,GHS06,GHS08]
Hazard Statement modified from
[H350 May cause cancer;
H340 May cause genetic defects;
H330 Fatal if inhaled;
H311 Toxic in contact with skin;
H301 Toxic if swallowed;
H314 Causes severe skin burns and eye damage]
to
[H350 May cause cancer;
H340 May cause genetic defects;
H314 Causes severe skin burns and eye damage;
H330 Fatal if inhaled;
H311 Toxic in contact with skin;
H301 Toxic if swallowed]
23/06/2016 Chemical Added