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| Cas Number | 32289-58-0 |
| Chemical Name | polyhexamethylene biguanide hydrochloride |
| Chemical Synonym |
PHMB |
| Hazard Category |
Carcinogenicity – category 2 Acute toxicity (inhalation) - category 2 Acute toxicity (ingestion) - category 4 Specific target organ toxicity (repeated exposure) – category 1 Eye damage – category 1 Skin sensitisation – category 1 Hazardous to the aquatic environment (acute) – category 1 Hazardous to the aquatic environment (chronic) – category 1 |
| Hazard Statement |
H351 (Suspected of causing cancer) H330 (Fatal if inhaled) H302 (Harmful if swallowed) H372 (Causes damage to the respiratory tract through prolonged or repeated inhalation) H318 (Causes serious eye damage) H317 (May cause an allergic skin reaction) H410 (Very toxic to aquatic life with long-lasting effects) |
| Pictogram |
GHS08 (Health Hazard) 
GHS06 (Skull and Crossbones) 
GHS05 (Corrosion) 
GHS09 (Environment) |
| Signal Word | Danger |
| Cut-offs | M = 10 (acute) |
| Notes |
8 (The tables in schedule 6 of the WHS regulations replace some tables in the GHS, this may affect the cut off concentrations for this chemical.) |
| Sources |
EU (Classification information for chemical is taken from the European Union’s Classification, Labelling and Packaging (CLP) Regulation.) N (The classification information for this entry was provided by the National Industrial Chemical Notification and Assessment Scheme) |
Hazardous Chemical History
| Date | Description |
|---|---|
| 03/05/2021 |
Hazard Category modified from [HC102:Carcinogenicity – category 2, HC065:Acute toxicity (inhalation) - category 2, HC072:Acute toxicity (ingestion) - category 4, HC111:Specific target organ toxicity (repeated exposure) – category 1, HC085:Eye damage – category 1, HC094:Skin sensitisation – category 1B, HC115:Hazardous to the aquatic environment (acute) – category 1, HC118:Hazardous to the aquatic environment (chronic) – category 1] to [HC065:Acute toxicity (inhalation) - category 2, HC072:Acute toxicity (ingestion) - category 4, HC085:Eye damage – category 1, HC092:Skin sensitisation – category 1, HC102:Carcinogenicity – category 2, HC111:Specific target organ toxicity (repeated exposure) – category 1, HC115:Hazardous to the aquatic environment (acute) – category 1, HC118:Hazardous to the aquatic environment (chronic) – category 1] Pictogram modified from [GHS08,GHS06,GHS05,GHS09] to [GHS05,GHS06,GHS08,GHS09] Sources modified from [EU] to [EU,N] |
| 03/05/2021 |
CutOffs modified from [M = 10 (acute) M = 10 (chronic)] to [ M = 10 (acute) Synonym modified from [] to [PHMB] Hazard Category modified from [HC102:Carcinogenicity – category 2, HC065:Acute toxicity (inhalation) - category 2, HC072:Acute toxicity (ingestion) - category 4, HC111:Specific target organ toxicity (repeated exposure) – category 1, HC085:Eye damage – category 1, HC094:Skin sensitisation – category 1B, HC115:Hazardous to the aquatic environment (acute) – category 1, HC118:Hazardous to the aquatic environment (chronic) – category 1] to [HC065:Acute toxicity (inhalation) - category 2, HC072:Acute toxicity (ingestion) - category 4, HC085:Eye damage – category 1, HC094:Skin sensitisation – category 1B, HC102:Carcinogenicity – category 2, HC111:Specific target organ toxicity (repeated exposure) – category 1, HC115:Hazardous to the aquatic environment (acute) – category 1, HC118:Hazardous to the aquatic environment (chronic) – category 1] Pictogram modified from [GHS08,GHS06,GHS05,GHS09] to [GHS05,GHS06,GHS08,GHS09] |
| 03/05/2021 |
CutOffs modified from [] to [M = 10 (acute) M = 10 (chronic)] Hazard Category modified from [HC102:Carcinogenicity – category 2, HC060:Acute toxicity – category 2, HC062:Acute toxicity – category 4, HC111:Specific target organ toxicity (repeated exposure) – category 1, HC085:Eye damage – category 1, HC094:Skin sensitisation – category 1B, HC115:Hazardous to the aquatic environment (acute) – category 1, HC118:Hazardous to the aquatic environment (chronic) – category 1] to [HC065:Acute toxicity (inhalation) - category 2, HC072:Acute toxicity (ingestion) - category 4, HC085:Eye damage – category 1, HC094:Skin sensitisation – category 1B, HC102:Carcinogenicity – category 2, HC111:Specific target organ toxicity (repeated exposure) – category 1, HC115:Hazardous to the aquatic environment (acute) – category 1, HC118:Hazardous to the aquatic environment (chronic) – category 1] Pictogram modified from [GHS08,GHS06,GHS05,GHS09] to [GHS05,GHS06,GHS08,GHS09] |
| 05/06/2018 |
Hazard Category modified from [HC102:Carcinogenicity – category 2, HC062:Acute toxicity – category 4, HC111:Specific target organ toxicity (repeated exposure) – category 1, HC085:Eye damage – category 1, HC094:Skin sensitisation – category 1B, HC115:Hazardous to the aquatic environment (acute) – category 1, HC118:Hazardous to the aquatic environment (chronic) – category 1] to [HC102:Carcinogenicity – category 2, HC060:Acute toxicity – category 2, HC062:Acute toxicity – category 4, HC111:Specific target organ toxicity (repeated exposure) – category 1, HC085:Eye damage – category 1, HC094:Skin sensitisation – category 1B, HC115:Hazardous to the aquatic environment (acute) – category 1, HC118:Hazardous to the aquatic environment (chronic) – category 1] Pictogram modified from [GHS05,GHS07,GHS08,GHS09] to [GHS08,GHS06,GHS05,GHS09] Hazard Statement modified from [H351 Suspected of causing cancer; H302 Harmful if swallowed; H372 Causes damage to the repiratory tract through prolonged or repeated inhalation; H318 Causes serious eye damage; H317 May cause an allergic skin reaction; H410 Very toxic to aquatic life with long-lasting effects] to [H351 ; H330 ; H302 ; H372 Causes damage to the respiratory tract through prolonged or repeated inhalation; H318 ; H317 ; H410 ] |
| 20/12/2016 | Chemical Added |