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Hazardous Chemical Details

Cas Number 65321-67-7
Chemical Name 1,3-Benzenediamine, 4-methyl-, sulfate (1:1)
Chemical Synonym toluene-2,4-diammonium sulphate
4-methyl-mphenylenediamine sulfate
toluene-2,4-diammonium sulfate
Hazard Category Carcinogenicity – category 1B
Germ cell mutagenicity – category 2
Specific target organ toxicity (repeated exposure) – category 2
Reproductive toxicity – category 2
Skin sensitisation – category 1
Eye irritation – category 2A
Hazardous to the aquatic environment (chronic) – category 2
Acute toxicity (ingestion) - category 3
Acute toxicity (dermal) - category 4
Hazard Statement H350 (May cause cancer)
H341 (Suspected of causing genetic defects)
H319 (Causes serious eye irritation)
H373 (May cause damage to organs through prolonged or repeated exposure)
H361f (Suspected of damaging fertility)
H317 (May cause an allergic skin reaction)
H411 (Toxic to aquatic life with long-lasting effects)
H301 (Toxic if swallowed)
H312 (Harmful in contact with skin)
Pictogram Pictogram of Skull and Crossbones GHS06 (Skull and Crossbones)
Pictogram of Health Hazard GHS08 (Health Hazard)
Pictogram of Environment GHS09 (Environment)
Signal Word Danger
Cut-offs
Notes 8 (The tables in schedule 6 of the WHS regulations replace some tables in the GHS, this may affect the cut off concentrations for this chemical.)
Sources EU (Classification information for chemical is taken from the European Union’s Classification, Labelling and Packaging (CLP) Regulation.)
A (The classification information for this entry was provided by the Australian Industrial Chemicals Introduction Scheme)

Hazardous Chemical History

Date Description
18/08/2021 Hazard Category modified from
[HC101:Carcinogenicity – category 1B,
HC098:Germ cell mutagenicity – category 2,
HC112:Specific target organ toxicity (repeated exposure) – category 2,
HC106:Reproductive toxicity – category 2,
HC092:Skin sensitisation – category 1,
HC087:Eye irritation – category 2A,
HC119:Hazardous to the aquatic environment (chronic) – category 2,
HC071:Acute toxicity (ingestion) - category 3,
HC077:Acute toxicity (dermal) - category 4]

to
[HC071:Acute toxicity (ingestion) - category 3,
HC077:Acute toxicity (dermal) - category 4,
HC087:Eye irritation – category 2A,
HC092:Skin sensitisation – category 1,
HC098:Germ cell mutagenicity – category 2,
HC101:Carcinogenicity – category 1B,
HC106:Reproductive toxicity – category 2,
HC112:Specific target organ toxicity (repeated exposure) – category 2,
HC119:Hazardous to the aquatic environment (chronic) – category 2]
18/08/2021 Hazard Category modified from
[HC101:Carcinogenicity – category 1B,
HC098:Germ cell mutagenicity – category 2,
HC112:Specific target organ toxicity (repeated exposure) – category 2,
HC106:Reproductive toxicity – category 2,
HC092:Skin sensitisation – category 1,
HC087:Eye irritation – category 2A,
HC119:Hazardous to the aquatic environment (chronic) – category 2,
HC071:Acute toxicity (ingestion) - category 3,
HC077:Acute toxicity (dermal) - category 4]

to
[HC071:Acute toxicity (ingestion) - category 3,
HC077:Acute toxicity (dermal) - category 4,
HC087:Eye irritation – category 2A,
HC092:Skin sensitisation – category 1,
HC098:Germ cell mutagenicity – category 2,
HC101:Carcinogenicity – category 1B,
HC106:Reproductive toxicity – category 2,
HC112:Specific target organ toxicity (repeated exposure) – category 2,
HC119:Hazardous to the aquatic environment (chronic) – category 2]
18/08/2021 Synonym modified from
[toluene-2,4-diammonium sulphate;
4-methyl-mphenylenediamine sulfate;
toluene-2,4-diammonium sulfate]
to
[toluene-2,4-diammonium sulphate;
4-methyl-mphenylenediamine sulfate;
toluene-2,4-diammonium sulfate]
Hazard Category modified from
[HC101:Carcinogenicity – category 1B,
HC098:Germ cell mutagenicity – category 2,
HC112:Specific target organ toxicity (repeated exposure) – category 2,
HC106:Reproductive toxicity – category 2,
HC092:Skin sensitisation – category 1,
HC087:Eye irritation – category 2A,
HC119:Hazardous to the aquatic environment (chronic) – category 2,
HC071:Acute toxicity (ingestion) - category 3,
HC077:Acute toxicity (dermal) - category 4]

to
[HC071:Acute toxicity (ingestion) - category 3,
HC077:Acute toxicity (dermal) - category 4,
HC087:Eye irritation – category 2A,
HC092:Skin sensitisation – category 1,
HC098:Germ cell mutagenicity – category 2,
HC101:Carcinogenicity – category 1B,
HC106:Reproductive toxicity – category 2,
HC112:Specific target organ toxicity (repeated exposure) – category 2,
HC119:Hazardous to the aquatic environment (chronic) – category 2]
18/08/2021 Hazard Category modified from
[HC061:Acute toxicity – category 3,
HC062:Acute toxicity – category 4,
HC101:Carcinogenicity – category 1B,
HC098:Germ cell mutagenicity – category 2,
HC112:Specific target organ toxicity (repeated exposure) – category 2,
HC106:Reproductive toxicity – category 2,
HC092:Skin sensitisation – category 1,
HC087:Eye irritation – category 2A,
HC119:Hazardous to the aquatic environment (chronic) – category 2]

to
[HC071:Acute toxicity (ingestion) - category 3,
HC077:Acute toxicity (dermal) - category 4,
HC087:Eye irritation – category 2A,
HC092:Skin sensitisation – category 1,
HC098:Germ cell mutagenicity – category 2,
HC101:Carcinogenicity – category 1B,
HC106:Reproductive toxicity – category 2,
HC112:Specific target organ toxicity (repeated exposure) – category 2,
HC119:Hazardous to the aquatic environment (chronic) – category 2]

Hazard Statement modified from
[H301 Toxic if swallowed;
H312 Harmful in contact with skin;
H350 May cause cancer;
H341 Suspected of causing genetic defects;
H319 Causes serious eye irritation;
H373 May cause damage to organs through prolonged or repeated exposure;
H361f Suspected of damaging fertility;
H317 May cause an allergic skin reaction;
H411 Toxic to aquatic life with long-lasting effects]
to
[H350 May cause cancer;
H341 Suspected of causing genetic defects;
H319 Causes serious eye irritation;
H373 May cause damage to organs through prolonged or repeated exposure;
H361f Suspected of damaging fertility;
H317 May cause an allergic skin reaction;
H411 Toxic to aquatic life with long-lasting effects;
H301 Toxic if swallowed;
H312 Harmful in contact with skin]
Sources modified from
[N,EU]
to
[EU,A]
26/07/2019 Synonym modified from
[toluene-2,4-diammonium sulphate;
4-methyl-mphenylenediamine sulfate]
to
[toluene-2,4-diammonium sulphate;
4-methyl-mphenylenediamine sulfate;
toluene-2,4-diammonium sulfate]
25/11/2016 Hazard Category modified from
[HC061:Acute toxicity – category 3,
HC062:Acute toxicity – category 4,
HC101:Carcinogenicity – category 1B,
HC098:Germ cell mutagenicity – category 2,
HC112:Specific target organ toxicity (repeated exposure) – category 2,
HC106:Reproductive toxicity – category 2,
HC092:Skin sensitisation – category 1]

to
[HC061:Acute toxicity – category 3,
HC062:Acute toxicity – category 4,
HC101:Carcinogenicity – category 1B,
HC098:Germ cell mutagenicity – category 2,
HC112:Specific target organ toxicity (repeated exposure) – category 2,
HC106:Reproductive toxicity – category 2,
HC092:Skin sensitisation – category 1,
HC087:Eye irritation – category 2A,
HC119:Hazardous to the aquatic environment (chronic) – category 2]
23/06/2016 Chemical Added



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