Hazardous Chemical Information System (HCIS)



Hazardous Chemical Details

Cas Number 81-81-2
Chemical Name warfarin (ISO)
Chemical Synonym 4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one
Hazard Category Reproductive toxicity – category 1A
Specific target organ toxicity (repeated exposure) – category 1
Hazardous to the aquatic environment (chronic) – category 2
Acute toxicity (ingestion) - category 2
Acute toxicity (inhalation) - category 1
Acute toxicity (dermal) - category 1
Hazard Statement H360D (May damage the unborn child)
H330 (Fatal if inhaled)
H310 (Fatal in contact with skin)
H300 (Fatal if swallowed)
H372 (Causes damage to the blood through prolonged or repeated exposure)
H411 (Toxic to aquatic life with long-lasting effects)
Pictogram Pictogram of Health Hazard GHS08 (Health Hazard)
Pictogram of Skull and Crossbones GHS06 (Skull and Crossbones)
Pictogram of Environment GHS09 (Environment)
Signal Word Danger
Cut-offs
Notes 8 (The tables in schedule 6 of the WHS regulations replace some tables in the GHS, this may affect the cut off concentrations for this chemical.)
Sources EU (Classification information for chemical is taken from the European Union’s Classification, Labelling and Packaging (CLP) Regulation.)

Hazardous Chemical History

Date Description
22/10/2019 Hazard Category modified from
[HC104:Reproductive toxicity – category 1A,
HC059:Acute toxicity – category 1,
HC059:Acute toxicity – category 1,
HC060:Acute toxicity – category 2,
HC111:Specific target organ toxicity (repeated exposure) – category 1,
HC119:Hazardous to the aquatic environment (chronic) – category 2]

to
[HC104:Reproductive toxicity – category 1A,
HC111:Specific target organ toxicity (repeated exposure) – category 1,
HC119:Hazardous to the aquatic environment (chronic) – category 2,
HC070:Acute toxicity (ingestion) - category 2,
HC064:Acute toxicity (inhalation) - category 1,
HC074:Acute toxicity (dermal) - category 1]

Pictogram modified from
[GHS08,GHS06,GHS09]
to
[GHS06,GHS08,GHS09]
05/06/2018 Synonym modified from
[]
to
[4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one]
Hazard Category modified from
[HC104:Reproductive toxicity – category 1A,
HC111:Specific target organ toxicity (repeated exposure) – category 1,
HC120:Hazardous to the aquatic environment (chronic) – category 3]

to
[HC104:Reproductive toxicity – category 1A,
HC059:Acute toxicity – category 1,
HC059:Acute toxicity – category 1,
HC060:Acute toxicity – category 2,
HC111:Specific target organ toxicity (repeated exposure) – category 1,
HC119:Hazardous to the aquatic environment (chronic) – category 2]

Pictogram modified from
[GHS08]
to
[GHS08,GHS06,GHS09]
Hazard Statement modified from
[H360D May damage the unborn child;
H372 Causes damage to organs through prolonged or repeated exposure;
H412 Harmful to aquatic life with long-lasting effects]
to
[H360D ;
H330 ;
H310 ;
H300 ;
H372 Causes damage to the blood through prolonged or repeated exposure;
H411 ]
23/06/2016 Chemical Added