Hazardous Chemical Information System (HCIS)



Hazardous Chemical Details

Cas Number 142-64-3
Chemical Name piperazine dihydrochloride
Chemical Synonym
Hazard Category Eye irritation – category 2A
Skin irritation – category 2
Specific target organ toxicity (single exposure) – category 1
Specific target organ toxicity (repeated exposure) – category 2
Respiratory sensitisation – category 1
Skin sensitisation – category 1
Hazardous to the aquatic environment (chronic) – category 3
Reproductive toxicity – category 2
Hazard Statement H319 (Causes serious eye irritation)
H315 (Causes skin irritation)
H370 (Causes damage to organs if swallowed)
H373 (May cause damage to organs through prolonged or repeated exposure if swallowed)
H334 (May cause allergy or asthma symptoms or breathing difficulties if inhaled)
H317 (May cause an allergic skin reaction)
H412 (Harmful to aquatic life with long-lasting effects)
H361fd (Suspected of damaging fertility. Suspected of damaging the unborn child)
Pictogram Pictogram of Health Hazard GHS08 (Health Hazard)
Signal Word Danger
Cut-offs
Notes 8 (The tables in schedule 6 of the WHS regulations replace some tables in the GHS, this may affect the cut off concentrations for this chemical.)
Sources N (The classification information for this entry was provided by the National Industrial Chemical Notification and Assessment Scheme)
EU (Classification information for chemical is taken from the European Union’s Classification, Labelling and Packaging (CLP) Regulation.)

Hazardous Chemical History

Date Description
25/06/2018 Hazard Category modified from
[HC087:Eye irritation – category 2A,
HC083:Skin irritation – category 2,
HC108:Specific target organ toxicity (single exposure) – category 1,
HC112:Specific target organ toxicity (repeated exposure) – category 2,
HC106:Reproductive toxicity – category 2,
HC089:Respiratory sensitisation – category 1,
HC092:Skin sensitisation – category 1,
HC120:Hazardous to the aquatic environment (chronic) – category 3]

to
[HC087:Eye irritation – category 2A,
HC083:Skin irritation – category 2,
HC108:Specific target organ toxicity (single exposure) – category 1,
HC112:Specific target organ toxicity (repeated exposure) – category 2,
HC089:Respiratory sensitisation – category 1,
HC092:Skin sensitisation – category 1,
HC120:Hazardous to the aquatic environment (chronic) – category 3,
HC106:Reproductive toxicity – category 2]

Hazard Statement modified from
[H319 Causes serious eye irritation;
H315 Causes skin irritation;
H370 Causes damage to organs if swallowed;
H373 May cause damage to organs through prolonged or repeated exposure if swallowed;
H361 Suspected of damaging fertility or the unborn child;
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled;
H317 May cause an allergic skin reaction;
H412 Harmful to aquatic life with long-lasting effects]
to
[H319 Causes serious eye irritation;
H315 Causes skin irritation;
H370 Causes damage to organs if swallowed;
H373 May cause damage to organs through prolonged or repeated exposure if swallowed;
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled;
H317 May cause an allergic skin reaction;
H412 Harmful to aquatic life with long-lasting effects;
H361fd Suspected of damaging fertility. Suspected of damaging the unborn child]
09/05/2018 Hazard Category modified from
[HC106:Reproductive toxicity – category 2,
HC086:Eye irritation – category 2,
HC083:Skin irritation – category 2,
HC089:Respiratory sensitisation – category 1,
HC120:Hazardous to the aquatic environment (chronic) – category 3,
HC092:Skin sensitisation – category 1]

to
[HC087:Eye irritation – category 2A,
HC083:Skin irritation – category 2,
HC108:Specific target organ toxicity (single exposure) – category 1,
HC112:Specific target organ toxicity (repeated exposure) – category 2,
HC106:Reproductive toxicity – category 2,
HC089:Respiratory sensitisation – category 1,
HC092:Skin sensitisation – category 1,
HC120:Hazardous to the aquatic environment (chronic) – category 3]

Pictogram modified from
[GHS08,GHS07]
to
[GHS08]
Hazard Statement modified from
[H361fd Suspected of damaging fertility. Suspected of damaging the unborn child;
H319 Causes serious eye irritation;
H315 Causes skin irritation;
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled;
H317 May cause an allergic skin reaction;
H412 Harmful to aquatic life with long-lasting effects]
to
[H319 ;
H315 ;
H370 Causes damage to organs if swallowed;
H373 May cause damage to organs through prolonged or repeated exposure if swallowed;
H361 ;
H334 ;
H317 ;
H412 ]
Sources modified from
[EU]
to
[N,EU]
25/11/2016 Hazard Category modified from
[HC106:Reproductive toxicity – category 2,
HC086:Eye irritation – category 2,
HC083:Skin irritation – category 2,
HC089:Respiratory sensitisation – category 1,
HC120:Hazardous to the aquatic environment (chronic) – category 3]

to
[HC106:Reproductive toxicity – category 2,
HC086:Eye irritation – category 2,
HC083:Skin irritation – category 2,
HC089:Respiratory sensitisation – category 1,
HC120:Hazardous to the aquatic environment (chronic) – category 3,
HC092:Skin sensitisation – category 1]

Pictogram modified from
[GHS08]
to
[GHS08,GHS07]
23/06/2016 Chemical Added