Hazardous Chemical Information System (HCIS)



Hazardous Chemical Details

Cas Number 57-57-8
Chemical Name beta-panolide
Chemical Synonym 1,3-propiolactone
2-Oxetanone
3-hydroxypropionic acid lactone
3-propanolide
hydracrylic acid beta-lactone
Hazard Category Carcinogenicity – category 1B
Germ cell mutagenicity – category 1B
Eye irritation – category 2A
Skin irritation – category 2
Skin sensitisation – category 1
Acute toxicity (ingestion) - category 3
Acute toxicity (inhalation) - category 1
Hazard Statement H350 (May cause cancer)
H340 (May cause genetic defects)
H319 (Causes serious eye irritation)
H315 (Causes skin irritation)
H317 (May cause an allergic skin reaction)
H301 (Toxic if swallowed)
H330 (Fatal if inhaled)
Pictogram Pictogram of Skull and Crossbones GHS06 (Skull and Crossbones)
Pictogram of Health Hazard GHS08 (Health Hazard)
Signal Word Danger
Cut-offs
Notes 8 (The tables in schedule 6 of the WHS regulations replace some tables in the GHS, this may affect the cut off concentrations for this chemical.)
Sources A (The classification information for this entry was provided by the Australian Industrial Chemicals Introduction Scheme)

Hazardous Chemical History

Date Description
18/08/2021 Synonym modified from
[1,3-propiolactone;
2-Oxetanone]
to
[1,3-propiolactone;
2-Oxetanone;
3-hydroxypropionic acid lactone ;
3-propanolide;
hydracrylic acid beta-lactone]
Hazard Category modified from
[HC101:Carcinogenicity – category 1B,
HC097:Germ cell mutagenicity – category 1B,
HC087:Eye irritation – category 2A,
HC083:Skin irritation – category 2,
HC092:Skin sensitisation – category 1,
HC071:Acute toxicity (ingestion) - category 3,
HC064:Acute toxicity (inhalation) - category 1]

to
[HC064:Acute toxicity (inhalation) - category 1,
HC071:Acute toxicity (ingestion) - category 3,
HC083:Skin irritation – category 2,
HC087:Eye irritation – category 2A,
HC092:Skin sensitisation – category 1,
HC097:Germ cell mutagenicity – category 1B,
HC101:Carcinogenicity – category 1B]
18/08/2021 Hazard Category modified from
[HC061:Acute toxicity – category 3,
HC059:Acute toxicity – category 1,
HC101:Carcinogenicity – category 1B,
HC097:Germ cell mutagenicity – category 1B,
HC087:Eye irritation – category 2A,
HC083:Skin irritation – category 2,
HC092:Skin sensitisation – category 1]

to
[HC064:Acute toxicity (inhalation) - category 1,
HC071:Acute toxicity (ingestion) - category 3,
HC083:Skin irritation – category 2,
HC087:Eye irritation – category 2A,
HC092:Skin sensitisation – category 1,
HC097:Germ cell mutagenicity – category 1B,
HC101:Carcinogenicity – category 1B]

Hazard Statement modified from
[H301 Toxic if swallowed;
H330 Fatal if inhaled;
H350 May cause cancer;
H340 May cause genetic defects;
H319 Causes serious eye irritation;
H315 Causes skin irritation;
H317 May cause an allergic skin reaction]
to
[H350 May cause cancer;
H340 May cause genetic defects;
H319 Causes serious eye irritation;
H315 Causes skin irritation;
H317 May cause an allergic skin reaction;
H301 Toxic if swallowed;
H330 Fatal if inhaled]
Sources modified from
[N]
to
[A]
09/05/2018 Synonym modified from
[ 1,3-propiolactone]
to
[1,3-propiolactone;
2-Oxetanone]
Hazard Category modified from
[HC101:Carcinogenicity – category 1B,
HC060:Acute toxicity – category 2,
HC086:Eye irritation – category 2,
HC083:Skin irritation – category 2]

to
[HC061:Acute toxicity – category 3,
HC059:Acute toxicity – category 1,
HC101:Carcinogenicity – category 1B,
HC097:Germ cell mutagenicity – category 1B,
HC087:Eye irritation – category 2A,
HC083:Skin irritation – category 2,
HC092:Skin sensitisation – category 1]

Hazard Statement modified from
[H350 May cause cancer;
H330 Fatal if inhaled;
H319 Causes serious eye irritation;
H315 Causes skin irritation]
to
[H301 ;
H330 ;
H350 ;
H340 ;
H319 ;
H315 ;
H317 ]
Sources modified from
[EU]
to
[N]
23/06/2016 Chemical Added