Hazardous Chemical Information System (HCIS)



Hazardous Chemical Details

Cas Number 1327-53-3
Chemical Name Arsenic oxide (As2O3)
Chemical Synonym Diarsenic trioxide
Arsenic trioxide
Arsenious Acid Anhydride
Arsenite
Arsenolite
Trisenox
Hazard Category Carcinogenicity – category 1A
Germ cell mutagenicity – category 2
Specific target organ toxicity (repeated exposure) – category 1
Hazardous to the aquatic environment (acute) – category 1
Hazardous to the aquatic environment (chronic) – category 1
Skin corrosion – category 1
Acute toxicity (ingestion) - category 2
Acute toxicity (inhalation) - category 3
Hazard Statement H350 (May cause cancer)
H341 (Suspected of causing genetic defects)
H314 (Causes severe skin burns and eye damage)
H372 (Causes damage to organs through prolonged or repeated exposure)
H410 (Very toxic to aquatic life with long-lasting effects)
H300 (Fatal if swallowed)
H331 (Toxic if inhaled)
Pictogram Pictogram of Skull and Crossbones GHS06 (Skull and Crossbones)
Pictogram of Health Hazard GHS08 (Health Hazard)
Pictogram of Corrosion GHS05 (Corrosion)
Pictogram of Environment GHS09 (Environment)
Signal Word Danger
Cut-offs
Notes 8 (The tables in schedule 6 of the WHS regulations replace some tables in the GHS, this may affect the cut off concentrations for this chemical.)
Sources EU (Classification information for chemical is taken from the European Union’s Classification, Labelling and Packaging (CLP) Regulation.)
A (The classification information for this entry was provided by the Australian Industrial Chemicals Introduction Scheme)

Hazardous Chemical History

Date Description
18/08/2021 Synonym modified from
[Diarsenic trioxide;
Arsenic trioxide]
to
[Diarsenic trioxide;
Arsenic trioxide;
Arsenious Acid Anhydride ;
Arsenite ;
Arsenolite ;
Trisenox ]
Hazard Category modified from
[HC100:Carcinogenicity – category 1A,
HC098:Germ cell mutagenicity – category 2,
HC111:Specific target organ toxicity (repeated exposure) – category 1,
HC115:Hazardous to the aquatic environment (acute) – category 1,
HC118:Hazardous to the aquatic environment (chronic) – category 1,
HC079:Skin corrosion – category 1,
HC070:Acute toxicity (ingestion) - category 2,
HC066:Acute toxicity (inhalation) - category 3]

to
[HC066:Acute toxicity (inhalation) - category 3,
HC070:Acute toxicity (ingestion) - category 2,
HC079:Skin corrosion – category 1,
HC098:Germ cell mutagenicity – category 2,
HC100:Carcinogenicity – category 1A,
HC111:Specific target organ toxicity (repeated exposure) – category 1,
HC115:Hazardous to the aquatic environment (acute) – category 1,
HC118:Hazardous to the aquatic environment (chronic) – category 1]

Pictogram modified from
[GHS06,GHS08,GHS05,GHS09]
to
[GHS05,GHS06,GHS08,GHS09]
18/08/2021 Hazard Category modified from
[HC060:Acute toxicity – category 2,
HC061:Acute toxicity – category 3,
HC100:Carcinogenicity – category 1A,
HC098:Germ cell mutagenicity – category 2,
HC111:Specific target organ toxicity (repeated exposure) – category 1,
HC115:Hazardous to the aquatic environment (acute) – category 1,
HC118:Hazardous to the aquatic environment (chronic) – category 1,
HC079:Skin corrosion – category 1]

to
[HC066:Acute toxicity (inhalation) - category 3,
HC070:Acute toxicity (ingestion) - category 2,
HC079:Skin corrosion – category 1,
HC098:Germ cell mutagenicity – category 2,
HC100:Carcinogenicity – category 1A,
HC111:Specific target organ toxicity (repeated exposure) – category 1,
HC115:Hazardous to the aquatic environment (acute) – category 1,
HC118:Hazardous to the aquatic environment (chronic) – category 1]

Pictogram modified from
[GHS06,GHS08,GHS05,GHS09]
to
[GHS05,GHS06,GHS08,GHS09]
Hazard Statement modified from
[H300 Fatal if swallowed;
H331 Toxic if inhaled;
H350 May cause cancer;
H341 Suspected of causing genetic defects;
H314 Causes severe skin burns and eye damage;
H372 Causes damage to organs through prolonged or repeated exposure;
H410 Very toxic to aquatic life with long-lasting effects]
to
[H350 May cause cancer;
H341 Suspected of causing genetic defects;
H314 Causes severe skin burns and eye damage;
H372 Causes damage to organs through prolonged or repeated exposure;
H410 Very toxic to aquatic life with long-lasting effects;
H300 Fatal if swallowed;
H331 Toxic if inhaled]
Sources modified from
[N,EU]
to
[EU,A]
25/11/2016 Hazard Category modified from
[HC060:Acute toxicity – category 2,
HC061:Acute toxicity – category 3,
HC100:Carcinogenicity – category 1A,
HC098:Germ cell mutagenicity – category 2,
HC111:Specific target organ toxicity (repeated exposure) – category 1,
HC115:Hazardous to the aquatic environment (acute) – category 1,
HC118:Hazardous to the aquatic environment (chronic) – category 1]

to
[HC060:Acute toxicity – category 2,
HC061:Acute toxicity – category 3,
HC100:Carcinogenicity – category 1A,
HC098:Germ cell mutagenicity – category 2,
HC111:Specific target organ toxicity (repeated exposure) – category 1,
HC115:Hazardous to the aquatic environment (acute) – category 1,
HC118:Hazardous to the aquatic environment (chronic) – category 1,
HC079:Skin corrosion – category 1]
23/06/2016 Chemical Added