Hazardous Chemical Information System (HCIS)



Hazardous Chemical Details

Cas Number 584-84-9
Chemical Name 4-methyl-m-phenylene diisocyanate
Chemical Synonym toluene-2,4-diisocyanate
Benzene, 2,4-diisocyanato-1-methyl-
2,4-TDI
4-Methyl-meta-phenylene diisocyanate
1,3-Diisocyanato-4-methylbenzene
Hazard Category Carcinogenicity – category 2
Acute toxicity – category 1
Eye irritation – category 2A
Specific target organ toxicity (single exposure) – category 3
Respiratory sensitisation – category 1
Skin sensitisation – category 1
Hazardous to the aquatic environment (chronic) – category 3
Skin irritation – category 2
Hazard Statement H351 (Suspected of causing cancer)
H330 (Fatal if inhaled)
H319 (Causes serious eye irritation)
H335 (May cause respiratory irritation)
H315 (Causes skin irritation)
H334 (May cause allergy or asthma symptoms or breathing difficulties if inhaled)
H317 (May cause an allergic skin reaction)
H412 (Harmful to aquatic life with long-lasting effects)
Pictogram Pictogram of Skull and Crossbones GHS06 (Skull and Crossbones)
Pictogram of Health Hazard GHS08 (Health Hazard)
Signal Word Danger
Cut-offs

Respiratory sensitisation - category 1 (H334): concentration >= 0.1%

Notes C (Some organic substances may be marketed either in a specific isomeric form or as a mixture of several isomers.In this case the supplier should state on the label whether the substance is a specific isomer or a mixture of isomers.)
8 (The tables in schedule 6 of the WHS regulations replace some tables in the GHS, this may affect the cut off concentrations for this chemical.)
17 (Generic cut off concentrations also apply to this chemical in addition to the specific cut off concentration(s) above. Refer to the generic cut off concentration table on the Reference Information page of HCIS (http://hcis.safeworkaustralia.gov.au/UserGuide).)
Sources N (The classification information for this entry was provided by the National Industrial Chemical Notification and Assessment Scheme)
EU (Classification information for chemical is taken from the European Union’s Classification, Labelling and Packaging (CLP) Regulation.)

Hazardous Chemical History

Date Description
30/04/2021 CutOffs modified from
[]
to
[

Respiratory sensitisation - category 1 (H334): concentration >= 0.1%

]
Synonym modified from
[ toluene-2,6-di-isocyanate;
Benzene, 2,4-diisocyanato-1-methyl-]
to
[ toluene-2,4-diisocyanate;
Benzene, 2,4-diisocyanato-1-methyl-;
2,4-TDI;
4-Methyl-meta-phenylene diisocyanate;
1,3-Diisocyanato-4-methylbenzene ]
Hazard Category modified from
[HC102:Carcinogenicity – category 2,
HC059:Acute toxicity – category 1,
HC087:Eye irritation – category 2A,
HC110:Specific target organ toxicity (single exposure) – category 3,
HC089:Respiratory sensitisation – category 1,
HC092:Skin sensitisation – category 1,
HC120:Hazardous to the aquatic environment (chronic) – category 3,
HC083:Skin irritation – category 2]

to
[HC059:Acute toxicity – category 1,
HC083:Skin irritation – category 2,
HC087:Eye irritation – category 2A,
HC089:Respiratory sensitisation – category 1,
HC092:Skin sensitisation – category 1,
HC102:Carcinogenicity – category 2,
HC110:Specific target organ toxicity (single exposure) – category 3,
HC120:Hazardous to the aquatic environment (chronic) – category 3]

Notes modified from
[C ,8 ]
to
[C ,8 ,17 ]
25/11/2016 Hazard Category modified from
[HC102:Carcinogenicity – category 2,
HC059:Acute toxicity – category 1,
HC087:Eye irritation – category 2A,
HC110:Specific target organ toxicity (single exposure) – category 3,
HC089:Respiratory sensitisation – category 1,
HC092:Skin sensitisation – category 1,
HC120:Hazardous to the aquatic environment (chronic) – category 3]

to
[HC102:Carcinogenicity – category 2,
HC059:Acute toxicity – category 1,
HC087:Eye irritation – category 2A,
HC110:Specific target organ toxicity (single exposure) – category 3,
HC089:Respiratory sensitisation – category 1,
HC092:Skin sensitisation – category 1,
HC120:Hazardous to the aquatic environment (chronic) – category 3,
HC083:Skin irritation – category 2]
23/06/2016 Chemical Added