Hazardous Chemical Information System (HCIS)



Hazardous Chemical Details

Cas Number 75-21-8
Chemical Name ethylene oxide
Chemical Synonym oxirane
oxacyclopropane
dihydrooxirene
dimethylene oxide
epoxyethane
1,2-epoxyethane
Hazard Category Gases under pressure
Flammable gas – category 1
Carcinogenicity – category 1B
Germ cell mutagenicity – category 1B
Skin corrosion – category 1B
Specific target organ toxicity (repeated exposure) – category 1
Skin sensitisation – category 1
Acute toxicity (ingestion) - category 4
Acute toxicity (inhalation) - category 3
Hazard Statement H220 (Extremely flammable gas)
H350 (May cause cancer)
H340 (May cause genetic defects)
H314 (Causes severe skin burns and eye damage)
H372 (Causes damage to organs through prolonged or repeated exposure through inhalation)
H317 (May cause an allergic skin reaction)
H302 (Harmful if swallowed)
H331 (Toxic if inhaled)
Pictogram Pictogram of Gas Cylinder GHS04 (Gas Cylinder)
Pictogram of 
Flame
GHS02 ( Flame )
Pictogram of Skull and Crossbones GHS06 (Skull and Crossbones)
Pictogram of Health Hazard GHS08 (Health Hazard)
Pictogram of Corrosion GHS05 (Corrosion)
Signal Word
Cut-offs
Notes 8 (The tables in schedule 6 of the WHS regulations replace some tables in the GHS, this may affect the cut off concentrations for this chemical.)
U (When put on the market gases should be classified as ‘Gases under pressure’, in one of the groups compressed gas, liquefied gas, refrigerated liquefied gas or dissolved gas. The group depends on the physical state in which the gas is packaged and therefore has to be assigned case by case.)
Sources EU (Classification information for chemical is taken from the European Union’s Classification, Labelling and Packaging (CLP) Regulation.)
A (The classification information for this entry was provided by the Australian Industrial Chemicals Introduction Scheme)

Hazardous Chemical History

Date Description
18/08/2021 Synonym modified from
[ oxirane;
oxacyclopropane ;
dihydrooxirene;
dimethylene oxide;
epoxyethane;
1,2-epoxyethane]
to
[ oxirane;
oxacyclopropane ;
dihydrooxirene;
dimethylene oxide;
epoxyethane;
1,2-epoxyethane]
Hazard Category modified from
[HC020:Gases under pressure,
HC009:Flammable gas – category 1,
HC101:Carcinogenicity – category 1B,
HC097:Germ cell mutagenicity – category 1B,
HC081:Skin corrosion – category 1B,
HC111:Specific target organ toxicity (repeated exposure) – category 1,
HC092:Skin sensitisation – category 1,
HC072:Acute toxicity (ingestion) - category 4,
HC066:Acute toxicity (inhalation) - category 3]

to
[HC009:Flammable gas – category 1,
HC020:Gases under pressure,
HC066:Acute toxicity (inhalation) - category 3,
HC072:Acute toxicity (ingestion) - category 4,
HC081:Skin corrosion – category 1B,
HC092:Skin sensitisation – category 1,
HC097:Germ cell mutagenicity – category 1B,
HC101:Carcinogenicity – category 1B,
HC111:Specific target organ toxicity (repeated exposure) – category 1]

Pictogram modified from
[]
to
[GHS02,GHS04,GHS05,GHS06,GHS08]
Notes modified from
[]
to
[U ,8 ]
18/08/2021 Signal Word modified from
[Danger]
to
[]
Synonym modified from
[ oxirane]
to
[ oxirane;
oxacyclopropane ;
dihydrooxirene;
dimethylene oxide;
epoxyethane;
1,2-epoxyethane]
Hazard Category modified from
[HC020:Gases under pressure,
HC009:Flammable gas – category 1,
HC062:Acute toxicity – category 4,
HC061:Acute toxicity – category 3,
HC101:Carcinogenicity – category 1B,
HC097:Germ cell mutagenicity – category 1B,
HC081:Skin corrosion – category 1B,
HC111:Specific target organ toxicity (repeated exposure) – category 1,
HC092:Skin sensitisation – category 1]

to
[HC009:Flammable gas – category 1,
HC020:Gases under pressure,
HC066:Acute toxicity (inhalation) - category 3,
HC072:Acute toxicity (ingestion) - category 4,
HC081:Skin corrosion – category 1B,
HC092:Skin sensitisation – category 1,
HC097:Germ cell mutagenicity – category 1B,
HC101:Carcinogenicity – category 1B,
HC111:Specific target organ toxicity (repeated exposure) – category 1]

Pictogram modified from
[GHS04,GHS02,GHS06,GHS08,GHS05]
to
[]
Hazard Statement modified from
[H220 Extremely flammable gas;
H302 Harmful if swallowed;
H331 Toxic if inhaled;
H350 May cause cancer;
H340 May cause genetic defects;
H314 Causes severe skin burns and eye damage;
H372 Causes damage to organs through prolonged or repeated exposure if inhaled;
H317 May cause an allergic skin reaction]
to
[H220 Extremely flammable gas;
H350 May cause cancer;
H340 May cause genetic defects;
H314 Causes severe skin burns and eye damage;
H372 Causes damage to organs through prolonged or repeated exposure through inhalation;
H317 May cause an allergic skin reaction;
H302 Harmful if swallowed;
H331 Toxic if inhaled]
Notes modified from
[U ,8 ]
to
[]
Sources modified from
[N,EU]
to
[EU,A]
09/05/2018 Synonym modified from
[ oxirane]
to
[ oxirane]
Hazard Category modified from
[HC020:Gases under pressure,
HC009:Flammable gas – category 1,
HC101:Carcinogenicity – category 1B,
HC097:Germ cell mutagenicity – category 1B,
HC086:Eye irritation – category 2,
HC110:Specific target organ toxicity (single exposure) – category 3,
HC083:Skin irritation – category 2,
HC061:Acute toxicity – category 3]

to
[HC020:Gases under pressure,
HC009:Flammable gas – category 1,
HC062:Acute toxicity – category 4,
HC061:Acute toxicity – category 3,
HC101:Carcinogenicity – category 1B,
HC097:Germ cell mutagenicity – category 1B,
HC081:Skin corrosion – category 1B,
HC111:Specific target organ toxicity (repeated exposure) – category 1,
HC092:Skin sensitisation – category 1]

Pictogram modified from
[GHS02,GHS04,GHS06,GHS08]
to
[GHS04,GHS02,GHS06,GHS08,GHS05]
Hazard Statement modified from
[H220 Extremely flammable gas;
H350 May cause cancer;
H340 May cause genetic defects;
H331 Toxic if inhaled;
H319 Causes serious eye irritation;
H335 May cause respiratory irritation;
H315 Causes skin irritation]
to
[H220 ;
H302 ;
H331 ;
H350 ;
H340 ;
H314 ;
H372 Causes damage to organs through prolonged or repeated exposure if inhaled;
H317 ]
Notes modified from
[8]
to
[U,8]
Sources modified from
[EU]
to
[N,EU]
25/11/2016 Hazard Category modified from
[HC020:Gases under pressure,
HC009:Flammable gas – category 1,
HC101:Carcinogenicity – category 1B,
HC097:Germ cell mutagenicity – category 1B,
HC086:Eye irritation – category 2,
HC110:Specific target organ toxicity (single exposure) – category 3,
HC083:Skin irritation – category 2]

to
[HC020:Gases under pressure,
HC009:Flammable gas – category 1,
HC101:Carcinogenicity – category 1B,
HC097:Germ cell mutagenicity – category 1B,
HC086:Eye irritation – category 2,
HC110:Specific target organ toxicity (single exposure) – category 3,
HC083:Skin irritation – category 2,
HC061:Acute toxicity – category 3]
23/06/2016 Chemical Added