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| Cas Number | 556-52-5 |
| Chemical Name | 2,3-epoxypropan-1-ol |
| Chemical Synonym |
glycidol oxiranemethanol 2-hydroxymethyloxirane 1-hydroxy-2,3-epoxypropane 1,2-epoxy-3-hydroxypropane |
| Hazard Category |
Carcinogenicity – category 1B Germ cell mutagenicity – category 1B Eye irritation – category 2A Skin irritation – category 2 Specific target organ toxicity (single exposure) – category 3 Reproductive toxicity – category 1B Acute toxicity (ingestion) - category 4 Acute toxicity (dermal) - category 4 Acute toxicity (inhalation) - category 2 |
| Hazard Statement |
H350 (May cause cancer) H340 (May cause genetic defects) H319 (Causes serious eye irritation) H315 (Causes skin irritation) H335 (May cause respiratory irritation) H360F (May damage fertility) H302 (Harmful if swallowed) H312 (Harmful in contact with skin) H330 (Fatal if inhaled) |
| Pictogram |
GHS06 (Skull and Crossbones) 
GHS08 (Health Hazard) |
| Signal Word | Danger |
| Cut-offs | |
| Notes |
8 (The tables in schedule 6 of the WHS regulations replace some tables in the GHS, this may affect the cut off concentrations for this chemical.) |
| Sources |
A (The classification information for this entry was provided by the Australian Industrial Chemicals Introduction Scheme) |
Hazardous Chemical History
| Date | Description |
|---|---|
| 18/08/2021 |
Synonym modified from [glycidol; oxiranemethanol] to [glycidol; oxiranemethanol; 2-hydroxymethyloxirane ; 1-hydroxy-2,3-epoxypropane ; 1,2-epoxy-3-hydroxypropane ] Hazard Category modified from [HC101:Carcinogenicity – category 1B, HC097:Germ cell mutagenicity – category 1B, HC087:Eye irritation – category 2A, HC083:Skin irritation – category 2, HC110:Specific target organ toxicity (single exposure) – category 3, HC105:Reproductive toxicity – category 1B, HC072:Acute toxicity (ingestion) - category 4, HC077:Acute toxicity (dermal) - category 4, HC065:Acute toxicity (inhalation) - category 2] to [HC065:Acute toxicity (inhalation) - category 2, HC072:Acute toxicity (ingestion) - category 4, HC077:Acute toxicity (dermal) - category 4, HC083:Skin irritation – category 2, HC087:Eye irritation – category 2A, HC097:Germ cell mutagenicity – category 1B, HC101:Carcinogenicity – category 1B, HC105:Reproductive toxicity – category 1B, HC110:Specific target organ toxicity (single exposure) – category 3] |
| 18/08/2021 |
Hazard Category modified from [HC062:Acute toxicity – category 4, HC062:Acute toxicity – category 4, HC060:Acute toxicity – category 2, HC101:Carcinogenicity – category 1B, HC097:Germ cell mutagenicity – category 1B, HC087:Eye irritation – category 2A, HC083:Skin irritation – category 2, HC110:Specific target organ toxicity (single exposure) – category 3, HC105:Reproductive toxicity – category 1B] to [HC065:Acute toxicity (inhalation) - category 2, HC072:Acute toxicity (ingestion) - category 4, HC077:Acute toxicity (dermal) - category 4, HC083:Skin irritation – category 2, HC087:Eye irritation – category 2A, HC097:Germ cell mutagenicity – category 1B, HC101:Carcinogenicity – category 1B, HC105:Reproductive toxicity – category 1B, HC110:Specific target organ toxicity (single exposure) – category 3] Hazard Statement modified from [H302 Harmful if swallowed; H312 Harmful in contact with skin; H330 Fatal if inhaled; H350 May cause cancer; H340 May cause genetic defects; H319 Causes serious eye irritation; H315 Causes skin irritation; H335 May cause respiratory irritation; H360F May damage fertility] to [H350 May cause cancer; H340 May cause genetic defects; H319 Causes serious eye irritation; H315 Causes skin irritation; H335 May cause respiratory irritation; H360F May damage fertility; H302 Harmful if swallowed; H312 Harmful in contact with skin; H330 Fatal if inhaled] Sources modified from [N] to [A] |
| 09/05/2018 |
Synonym modified from [ glycidol; oxiranemethanol] to [glycidol; oxiranemethanol] Hazard Category modified from [HC101:Carcinogenicity – category 1B, HC098:Germ cell mutagenicity – category 2, HC105:Reproductive toxicity – category 1B, HC061:Acute toxicity – category 3, HC062:Acute toxicity – category 4, HC086:Eye irritation – category 2, HC110:Specific target organ toxicity (single exposure) – category 3, HC083:Skin irritation – category 2] to [HC062:Acute toxicity – category 4, HC062:Acute toxicity – category 4, HC060:Acute toxicity – category 2, HC101:Carcinogenicity – category 1B, HC097:Germ cell mutagenicity – category 1B, HC087:Eye irritation – category 2A, HC083:Skin irritation – category 2, HC110:Specific target organ toxicity (single exposure) – category 3, HC105:Reproductive toxicity – category 1B] Hazard Statement modified from [H350 May cause cancer; H341 Suspected of causing genetic defects; H360F May damage fertility; H331 Toxic if inhaled; H312 Harmful in contact with skin; H302 Harmful if swallowed; H319 Causes serious eye irritation; H335 May cause respiratory irritation; H315 Causes skin irritation] to [H302 ; H312 ; H330 ; H350 ; H340 ; H319 ; H315 ; H335 ; H360F ] Sources modified from [EU] to [N] |
| 25/11/2016 |
Hazard Category modified from [HC101:Carcinogenicity – category 1B, HC098:Germ cell mutagenicity – category 2, HC105:Reproductive toxicity – category 1B, HC061:Acute toxicity – category 3, HC062:Acute toxicity – category 4, HC086:Eye irritation – category 2, HC110:Specific target organ toxicity (single exposure) – category 3] to [HC101:Carcinogenicity – category 1B, HC098:Germ cell mutagenicity – category 2, HC105:Reproductive toxicity – category 1B, HC061:Acute toxicity – category 3, HC062:Acute toxicity – category 4, HC086:Eye irritation – category 2, HC110:Specific target organ toxicity (single exposure) – category 3, HC083:Skin irritation – category 2] |
| 23/06/2016 | Chemical Added |