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| Cas Number | 101-77-9 |
| Chemical Name | 4,4'-diaminodiphenylmethane |
| Chemical Synonym |
4,4'-methylenedianiline Benzenamine, 4,4'-methylenebis- |
| Hazard Category |
Specific target organ toxicity (single exposure) – category 1 Carcinogenicity – category 1B Germ cell mutagenicity – category 2 Specific target organ toxicity (repeated exposure) – category 2 Skin sensitisation – category 1 Hazardous to the aquatic environment (chronic) – category 2 |
| Hazard Statement |
H370 (Causes damage to organs) H350 (May cause cancer) H341 (Suspected of causing genetic defects) H373 (May cause damage to organs through prolonged or repeated exposure) H317 (May cause an allergic skin reaction) H411 (Toxic to aquatic life with long-lasting effects) |
| Pictogram |
GHS08 (Health Hazard) 
GHS07 (Exclamation Mark) 
GHS09 (Environment) |
| Signal Word | Danger |
| Cut-offs | |
| Notes |
8 (The tables in schedule 6 of the WHS regulations replace some tables in the GHS, this may affect the cut off concentrations for this chemical.) |
| Sources |
N (The classification information for this entry was provided by the National Industrial Chemical Notification and Assessment Scheme) |
Hazardous Chemical History
| Date | Description |
|---|---|
| 07/04/2020 |
Hazard Category modified from [HC108:Specific target organ toxicity (single exposure) – category 1, HC101:Carcinogenicity – category 1B, HC096:Germ cell mutagenicity – category 1A, HC112:Specific target organ toxicity (repeated exposure) – category 2, HC092:Skin sensitisation – category 1, HC119:Hazardous to the aquatic environment (chronic) – category 2] to [HC108:Specific target organ toxicity (single exposure) – category 1, HC101:Carcinogenicity – category 1B, HC098:Germ cell mutagenicity – category 2, HC112:Specific target organ toxicity (repeated exposure) – category 2, HC092:Skin sensitisation – category 1, HC119:Hazardous to the aquatic environment (chronic) – category 2] Pictogram modified from [GHS08,GHS07,GHS09] to [GHS07,GHS08,GHS09] Hazard Statement modified from [H370 Causes damage to organs; H350 May cause cancer; H340 May cause genetic defects; H373 May cause damage to organs through prolonged or repeated exposure; H317 May cause an allergic skin reaction; H411 Toxic to aquatic life with long-lasting effects] to [H370 Causes damage to organs; H350 May cause cancer; H341 Suspected of causing genetic defects; H373 May cause damage to organs through prolonged or repeated exposure; H317 May cause an allergic skin reaction; H411 Toxic to aquatic life with long-lasting effects] |
| 09/05/2018 |
Synonym modified from [ 4,4'-methylenedianiline] to [4,4'-methylenedianiline; Benzenamine, 4,4'-methylenebis-] Hazard Category modified from [HC101:Carcinogenicity – category 1B, HC098:Germ cell mutagenicity – category 2, HC108:Specific target organ toxicity (single exposure) – category 1, HC112:Specific target organ toxicity (repeated exposure) – category 2, HC119:Hazardous to the aquatic environment (chronic) – category 2, HC092:Skin sensitisation – category 1] to [HC108:Specific target organ toxicity (single exposure) – category 1, HC101:Carcinogenicity – category 1B, HC096:Germ cell mutagenicity – category 1A, HC112:Specific target organ toxicity (repeated exposure) – category 2, HC092:Skin sensitisation – category 1, HC119:Hazardous to the aquatic environment (chronic) – category 2] Hazard Statement modified from [H350 May cause cancer; H341 Suspected of causing genetic defects; H370 Causes damage to organs; H373 May cause damage to organs through prolonged or repeated exposure; H317 May cause an allergic skin reaction; H411 Toxic to aquatic life with long-lasting effects] to [H370 ; H350 ; H340 ; H373 ; H317 ; H411 ] Sources modified from [EU] to [N] |
| 25/11/2016 |
Hazard Category modified from [HC101:Carcinogenicity – category 1B, HC098:Germ cell mutagenicity – category 2, HC108:Specific target organ toxicity (single exposure) – category 1, HC112:Specific target organ toxicity (repeated exposure) – category 2, HC119:Hazardous to the aquatic environment (chronic) – category 2] to [HC101:Carcinogenicity – category 1B, HC098:Germ cell mutagenicity – category 2, HC108:Specific target organ toxicity (single exposure) – category 1, HC112:Specific target organ toxicity (repeated exposure) – category 2, HC119:Hazardous to the aquatic environment (chronic) – category 2, HC092:Skin sensitisation – category 1] |
| 23/06/2016 | Chemical Added |